| First | Last | Nickname | Ht. | Wt. | Reach | Stance | W | L | D | Belt |
|---|---|---|---|---|---|---|---|---|---|---|
| Ray | Seraille | 6' 3" | 246 lbs. | -- | 8 | 9 | 0 | |||
| Ivan | Serati | 6' 0" | 205 lbs. | -- | Orthodox | 12 | 4 | 0 | ||
| Alex | Serdyukov | The Russian Crusher | 6' 2" | 170 lbs. | 74.0" | Orthodox | 8 | 5 | 0 | |
| Nicholas | Sergiacomi | -- | 170 lbs. | -- | 1 | 1 | 0 | |||
| Matt | Serra | The Terra | 5' 6" | 170 lbs. | 68.0" | Orthodox | 11 | 7 | 0 | |
| Nick | Serra | The Mad Monkey | 5' 9" | 170 lbs. | -- | Orthodox | 7 | 3 | 0 | |
| Adrian | Serrano | 5' 8" | 170 lbs. | -- | 56 | 29 | 4 | |||
| Fredy | Serrano | El Profe | 5' 3" | 125 lbs. | 65.0" | Orthodox | 3 | 2 | 0 | |
| Carl | Seumanutafa | 6' 1" | 255 lbs. | -- | Orthodox | 10 | 8 | 0 | ||
| Igor | Severino | 5' 7" | 125 lbs. | 69.0" | Orthodox | 8 | 1 | 0 | ||
| Dan | Severn | The Beast | 6' 2" | 250 lbs. | -- | Southpaw | 101 | 19 | 1 | |
| Rosi | Sexton | The Surgeon | 5' 3" | 135 lbs. | -- | Orthodox | 13 | 5 | 0 | |
| Rodrigo | Sezinando | 5' 9" | 170 lbs. | 71.0" | Orthodox | 9 | 2 | 0 | ||
| Scott | Shaffer | 5' 7" | 145 lbs. | -- | Orthodox | 0 | 1 | 0 | ||
| Edmen | Shahbazyan | The Golden Boy | 6' 2" | 185 lbs. | 75.0" | Orthodox | 16 | 5 | 0 | |
| Leon | Shahbazyan | 6' 4" | 170 lbs. | 74.0" | Orthodox | 7 | 2 | 0 | ||
| Don | Shainis | Shameless | 5' 6" | 145 lbs. | 67.0" | Orthodox | 12 | 5 | 0 | |
| Liliya | Shakirova | 5' 4" | 125 lbs. | 65.0" | Orthodox | 8 | 2 | 0 | ||
| Kamal | Shalorus | Prince of Persia | 5' 8" | 155 lbs. | 68.0" | Orthodox | 9 | 5 | 2 | |
| Ken | Shamrock | The World's Most Dangerous Man | 6' 1" | 205 lbs. | 72.0" | Orthodox | 28 | 17 | 2 | |
| Frank | Shamrock | 5' 10" | 185 lbs. | -- | Orthodox | 23 | 10 | 2 | ||
| Shang | Zhifa | Northeast Flying Tiger | 5' 7" | 125 lbs. | 63.0" | Orthodox | 32 | 8 | 0 | |
| Sean | Sharaf | The Smoke | 6' 3" | 252 lbs. | 77.0" | Orthodox | 4 | 1 | 0 | |
| Priya | Sharma | The Catwoman | 5' 1" | 115 lbs. | 59.0" | Orthodox | 5 | 2 | 0 |